PTPN11 and neoplasm: We identified missense mutations of BRAP (c.1109G > C, p.Gly370Ala) and PTPN11 (c.1508G > T, p.Gly503Val) in the tumor-derived subclones but not in the parental sNF96.2-GFP cells (Figure 2C,D; Figure S4A,B).