The reduced expression of cell adhesion proteins, such as SORBS3 (log2(FC) = −5.1), MCAM (log2(FC) = −6.0), or NECTIN3 (log2(FC) = −1.2), might result in de-adhesion and disturbed cell junction formation, thereby facilitating the dissemination of tumor cells from the tumor mass during the formation of metastases [31,32,33]. This evidence concerns the gene SORBS3 and neoplasm.