In addition, lncRNAs associated with the resistance to these cancer therapeutic drugs, for example, BORG, MALAT1, SBF2-AS1, HIF1A-AS1, LINC01134, NEAT1, LAMTOR5-AS1, NORAD, lincRNA-p21, ZFAS1 and MIAT, may also serve as promising biomarkers for the diagnosis of therapy-resistant cancers or the prediction of therapy outcome. The gene discussed is CDKN1A; the disease is cancer.