MBP and fetal growth restriction: Besides the morphological appearance, the gene expression of the OL lineage maturation markers Mbp and Mog was analyzed on day 5 in control and IUGR neurospheres without exposure or after exposure to T3 [3 nM] as a positive control (Figure 2G), since T3 is known to increase the OL maturation in human and rat neurospheres [21].