Evidence from postmortem studies indicated the relationship between alteration in the Akt and Erk signaling pathways and schizophrenia; there was a low level of AKT1 mRNA proteins in the cortex and the hippocampus [55], and there were some genetic variants of the AKT1 gene0020 that have been linked to schizophrenia [56]. The gene discussed is AKT1; the disease is schizophrenia.