Both the progression of psoriasis and the process of aging are associated with dysregulated immune cells and elevated levels of biomarkers of inflammation–such as C-reactive protein (CRP), tumor necrosis factor α (TNF-α), tumor necrosis factor β (TGF-β) and pro-inflammatory interleukins (including interleukin-6, IL-6)–enhanced expression and activity of matrix metalloproteinases, and neoangiogenesis [5,12,13,14,16,17,18,19]. Here, TNF is linked to psoriasis.