We identified PTSD-associated significant CpG sites in immune-related genes: IL-7R, CD34, CD8A and C1QL1 genes with differential 5mC; and IL-4R, IL-15, IL-21-AS1, TLR5 and TNFSF14 with differential 5hmC [Unpublished data]. The gene discussed is TLR5; the disease is post-traumatic stress disorder.