In this review, microglia markers such as DOCK2, as well as neuronal ionotropic and glutamate markers such as GRIN2B (Glutamate Ionotropic Receptor NMDA Type Subunit 2B) and SCN8A (sodium voltage-gated channel alpha subunit 1) were observed as dysregulated in PTSD. The gene discussed is SCN8A; the disease is post-traumatic stress disorder.