Other HIF-regulated genes implicated in GBM cell migration are ZEB1 (zinc finger E-box-binding homeobox 1), TWIST1 (Twist-related protein 1), and chemokines such as CXCR4 and its ligand CXCL12, and CCR5 and its ligand CCL4 [71,72], and now, we include ODZ1 as a relevant hypoxia-inducible factor in GSCs. The gene discussed is TWIST1; the disease is glioblastoma.