It has been reported that miR-15a enhances radiation sensitivity in lung cancer by regulating the TLR1/NF-κB signaling pathway [73], but also that its inhibition in response to high dose radiation (10 Gy and above) decreased cell proliferation, triggered apoptosis and inhibited angiogenesis in a murine colorectal carcinoma model [74]. The gene discussed is TLR1; the disease is colorectal carcinoma.