TNF and Alzheimer disease: Intriguingly, our cytokine-modulated hCS DEGs are clearly more related to the genes associated with the neuroinflammatory disease MS (33% and 28% overlap with TNFα-stimulated and IL-1β-stimulated hCS DEGs, respectively) than with AD (8% and 9%, respectively) or with PD (6% and 4%, respectively) (Figure 6E).