CTTN and Sepsis: As expected, CLP sepsis induced significant reduction in blood lymphocytes compared to sham-operated groups (Supplementary Figure S2A), but there was no significant difference between lymphocyte counts of septic WT mice (0.30 ± 0.06 × 109/L) compared to septic CTTN KO mice (0.28 ± 0.04 × 109/L).