TIMP1 and respiratory system disorder: The obtained results demonstrated that only 26 of 47 studied genes have been associated with mentioned respiratory disorders (Figure 2F), involving 9 of the top-10 hub genes revealed above by the network analysis (the most associated: Muc5ac, Ccl12 (human ortholog CCL2), Muc5b, Timp1; studied to a lesser extent: Ccl6 and Ccl9 (human ortholog CCL15), Cyp2e1, F5, and Adra2a).