Moreover, our analysis of the DisGeNET database demonstrated that Col4a1/2 and their unique partner genes are involved in the regulation of a range of disorders accompanied by fibrotic lesions, such as Alport syndrome, renal glomerular disease, fibrosing alveolitis, cirrhosis, as well as pulmonary fibrosis itself (Figure 7C). Here, COL4A1 is linked to idiopathic pulmonary fibrosis.