Finally, Cyp2e1 and Cat, DEGs downregulated in analyzed asthma-related GEO datasets (Figure 2), were significantly suppressed both in asthmatic and fibrotic lungs: Cat by 11.2- and 9.6-fold, respectively, and Cyp2e1 by 4.8- and 2.8-fold, respectively, compared with healthy control (Figure 5A). This evidence concerns the gene CYP2E1 and asthma.