MUC5AC and asthma: Our findings, firstly, show the adequate reliability of the results obtained by an in silico approach (revealed hub genes have already been widely studied in the field of asthma pathogenesis (Figure 2F)); secondly, they can be considered as a source of novel molecular markers of asthma and related disorders; and, thirdly, they clearly demonstrate that several acute asthma-associated key nodes, such as Muc5ac, Ccl12, Timp1, etc., can also be connected with the development of pulmonary fibrosis (Figure 2F).