Moreover, our analysis of the DisGeNET database demonstrated that Col4a1/2 and their unique partner genes are involved in the regulation of a range of disorders accompanied by fibrotic lesions, such as Alport syndrome, renal glomerular disease, fibrosing alveolitis, cirrhosis, as well as pulmonary fibrosis itself (Figure 7C). The gene discussed is COL4A1; the disease is Alport syndrome.