The comparison of gene markers of asthma and asthma-associated pulmonary fibrosis with key genes of allergy-independent bleomycin-induced fibrosis demonstrated low interconnection of asthma-related DEGs with bleomycin-perturbed regulome in murine lungs—only 11 genes were identified as common for both asthma/post-asthmatic fibrosis and bleomycin-induced fibrosis (Figure 6A, lower Venn diagram), among which three genes (Igf1, Spp1, Timp1) displayed the most obvious association with fibrotic process in lungs. The gene discussed is IGF1; the disease is fibrosis.