TM6SF2 and fibrosis: Our results confirm those of previous studies, namely PNPLA3 rs738409 and TM6SF2 rs58542926 alone (OR = 2.20; 95%CI 1.06–4.64; p = 0.036 and OR = 2.79; 95%CI 1.15–7.57; p = 0.031, respectively) or in combination (OR = 3.25; 95%CI 1.44–7.65; p = 0.005) were associated with significant risk of advanced fibrosis in our cohort.