ENSG00000161298 (ZNF382) belongs to the Krüppel-associated box (KRAB) domain zinc finger transcription factor (KZNF) family, which has been shown to regulate differentiation, proliferation and apoptosis processes and reduce the expression of matrix metallopeptidase 1 (MMP1) that is dysregulated in AMD [146,147]. This evidence concerns the gene MMP1 and age-related macular degeneration.