In addition, this miRNA set also regulates important AMD-related genes, such as VEGF-A, platelet-derived growth factor subunit A (PDGFA) and platelet-derived growth factor receptor α (PDGFRA), involved in the VEGF-signaling pathway, ECM–receptor interaction, cytokine–receptor interaction and the cell cycle [7]. The gene discussed is PDGFA; the disease is age-related macular degeneration.