Viral interference with the ubiquitous ACE2 (the primary cell entry receptor for the SARS-CoV-2), different degrees of endotheliitis, inappropriate immune responses, damage of the enteric vagal visceral afferents to the brain and hypothalamic-pituitary-adrenal axis, and dysbiosis interferes with post-COVID-19 dysautonomia [28,34,103]. This evidence concerns the gene ACE2 and dysautonomia.