The data by Bajetto et al. showed that MSC interactions (cocultures with glioma cells or releasing soluble factors) might produce a divergent effect from the inhibition of tumor growth to the strong production of molecules involved in inflammation, angiogenesis, cell migration, and proliferation, such as IL-8, GRO, ENA-78, and IL-6 [132]. Here, CXCL5 is linked to central nervous system cancer.