NRG1 and neurodegenerative disease: This is in contrast with data reported in numerous basic and clinical research studies indicating promising benefits from the administration of exogenous NRG1 in isolated hepatocytes, experimental models of cardiac regeneration or neurodegenerative diseases, and in heart-failure patients [8,75,76,77]; in steatotic and non-steatotic LT from DBDs, there were no observed benefits derived from the administration of NRG1.