Acute insulin resistance induced by tumor necrosis factor alpha (TNFα) or dexamethasone could be ameliorated by the antioxidants N-acetylcysteine, manganese (III) tetrakis (4-benzoicacid) porphyrin (MnTBAP), or by induction of antioxidant enzymes such as superoxide dismutase or catalase [6]. The gene discussed is TNF; the disease is Insulin resistance.