Additionally, the long non-coding RNA, HIF1A-AS2, OIP5-AS1, and CASC9 target IGF2BP2, both directly and indirectly, to facilitate the maintenance of mesenchymal glioblastoma stem-like cells [50], to repress resistance to TMZ and proliferation via OIP5-AS1-miR-129-5p axis [51], and to accelerate aerobic glycolysis by enhancing Hexokinase-2 (HK2) mRNA stability [52]. Here, HK2 is linked to glioblastoma.