CTLA4 and low grade glioma: At that time, high YTHDF2 expression was noted to be associated with poor overall survival in low-grade glioma (LGG) and positively correlated with several immune cells markers, including prephenate dehydratase 1 (PD-1), Hepatitis A virus cellular receptor 2 (HAVCR2/TIM-3), and cytotoxic T-lymphocyte associated protein 4 (CTLA-4), as well as TAM gene markers and IDH1 in these lesions [33].