CPT1B was upregulated in oxaliplatin-treated GC cells (HGC27 and MGC803), and the CPT1 inhibitor perhexiline and oxaliplatin inhibited tumor xenograft progression in a subcutaneous xenograft BALB/c nude mouse model of HGC27 cells, suggesting that CPT1-mediated fatty acid translocation and further fatty acid oxidation may be associated with oxaliplatin CPT1C expression was found to be substantially linked to poor DFS and OS in GC patients. The gene discussed is CPT1A; the disease is neoplasm.