Conversely, a high frequency of Asp358Ala variant was found in DVT patients with IL-6 levels higher than 3.465 pg/mL (i.e., the 75th percentile of IL-6 values in normal subjects) (DVT = 33.33%, control = 0%; OR > 20) (Table 2). The gene discussed is IL6; the disease is deep vein thrombosis.