Intraperitoneal injection of ES products resulted in reduced glucose levels and reduced body weight gain in a mouse model of T2D, and was accompanied by activation of eosinophilia and elevated IL-5, as well as a shift in the microbiota profile between the groups treated with ES products compared with untreated littermates fed both normal chow and high glycaemic index diets. Here, IL5 is linked to Increased total eosinophil count.