IL10 and colitis: Utilizing high-throughput sequencing techniques, it was demonstrated that inflammation is related to alterations in the gut microbial population in colitis-susceptible interleukin-10-deficient (Il10−/−) mice and that colonization of the intestine with commensal Escherichia coli NC101 triggers invasive carcinoma in Il10−/− mice treated with azoxymethane [3].