SIRT1 and Parkinson disease: Especially, SIRT1 can bind with several transcription factors, e.g., NF-κB, p65, retinoic acid receptor β (RARβ), forkhead box O (FOXO), and peroxisome proliferator-activated receptor-gamma coactivator 1α (PGC1α) associated with PD, and the activation of SIRT1 can maintain mitochondrial quantity and function and further reduce α-synuclein aggregation [77,78,79].