The gene expression levels of TRPC1, TRPC3, and TRPC5 were significantly higher in low-grade glioma (LGG), while the levels of TRPC4, TRPC6, TRPM7, MCOLN1, MCOLN2, and MCOLN3 were significantly higher in high-grade glioma (HGG). The gene discussed is TRPC4; the disease is glioma.