PLA2G6 and neurodegeneration with brain iron accumulation 2A: Since the identification of PLA2G6 mutations among two Israeli INAD families in 2006 [10], over 200 different mutations in PLAN patients have been identified in PLA2G6 according to the Human Gene Mutations Database (HGMD® Professional 2021.4, http://www.hgmd.org, accessed on 1 March 2022).