To determine the relevance of NRF2 in cell cycle progression, we knocked down NRF2 in U–373 MG glioblastoma–derived cells (Figure 1) and in two unrelated cell lines, U–87 MG (Figure S1A–C) and MDA–MB–231 (Figure S1D–F), that yielded similar results. Here, NFE2L2 is linked to glioblastoma.