In this paper, we demonstrate a correlation between Na concentration and SOD activity (infertile group: r = 0.309; control: r = 0.310; men with CC genotype regarding IL-4v.C589T (rs2243250) polymorphism: r = 0.500; Table 2 and Table 4), indicating a possible augmentation of antioxidative potential. Here, SOD1 is linked to Infertility.