With an increase in the volume of the tumor and an increase in the demand for nutrients and blood supply, to meet the needs of growth, the expression of tumor angiogenesis receptors such as the vascular endothelial growth factor, vascular endothelial growth factor receptor (VEGF/VEGFR) and integrin receptor αvβ3 increase significantly compared to in normal tissue [42]. The gene discussed is KDR; the disease is neoplasm.