PRMT5 and posterior cortical atrophy: In addition, correlation analysis revealed that circSPON2 expression negatively correlated with miR-331-3p expression (Fig. 8H; r = -0.5191, P < 0.01), whereas circSPON2 and PRMT5 expression levels (Fig. 8I; r = 0.4746, P < 0.01) exerted a positive correlation in our own cohort of 248 PCa patients.