VHL and nonpapillary renal cell carcinoma: Although, ccRCC patients with lower immune scores had prolonged overall survival than ccRCC patients with higher immune scores in TCGA dataset38, the immune scores was not associated with the clinical overalls survival of VHL mutant ccRCC in TCGA (Supplementary Fig. 1a) and E-MTAB-1980 (Supplementary Fig. 1b) datasets.