However, they were lower in viral controls (IL-6 4.61 pg/ml [IQR 2.09–16.51], CRP mg/l 3.3 [IQR 0.9–15.0], PCT 0.030 ng/ml [IQR 0.014–0.056]), than in COVID-19 with p-values again <0.001 for all comparisons. Here, CALCA is linked to COVID-19.