A previous study in rats, with 8 weeks of exposure to MPs (2–3 h/day), demonstrated a significant increase in the ECG variables (i.e., PR, QTc interval, and QRS duration), which was accompanied by the augmentation of renin activity and left ventricular hypertrophy with myocardial hypertrophy and alterations. Here, REN is linked to left ventricular hypertrophy.