Further, using a T-screen assay—a thyroid hormone-dependent rat pituitary tumor cell growth assay—Kambia et al. reported that MEHP and 5-OH-MEHP induced concentration dependent agonist activity in the cells stimulating cell growth, which was synergically enhanced by the addition of T3 [46]; however, 5-oxo-MEHP showed antagonistic and cytotoxic activity. The gene discussed is TG; the disease is pituitary tumor.