CAD and viral infectious disease: As described previously for crude polysaccharides [17], these results suggest that the antiviral effect of CPs could mainly be explained by interference with SARS-CoV-2 entry because propagation of SARS-CoV-2 was strongly inhibited and the virus titer sharply reduced when CPs were used to pretreat before viral infection (Figure 1 and Figure 2), while the inhibitory effect was less significant when CPs were used for post-treatment after viral infection (Figure 3 and Figure 4).