Studies with a clinical stage on the mitigation of liver health (ClinicalTrials.gov identifier: NCT03625284), the improvement of non-alcoholic fatty liver disease (ClinicalTrials.gov identifier: NCT02875392), metabolic syndrome of insulin sensitivity and secretion (ClinicalTrials.gov identifier: NCT03613740; phase 2), body weight management for overweight women (ClinicalTrials.gov identifier: NCT04761406), etc., have yet to publish their results. Here, INS is linked to metabolic syndrome.