DNMT3A and mature T-cell and NK-cell non-Hodgkin lymphoma: However, this LYSA study described an association between DNMT3A mutations and inferior PFS.140 The role of autologous stem cell transplantation (ASCT) for PTCL in first remission remains unresolved.141 A German and French co-led study randomised 104 PTCL patients to undergo either ASCT or alloSCT in first remission.