AIM2 and dilated cardiomyopathy: Recently, the expression of the sensors of the four major inflammasomes (the NLRP1, NLRP3, NLRC4 and AIM2 inflammasomes) in patients with HF was assessed, and it was found that the expression of the inflammasome proteins AIM2 and NLRC4 was increased in patients with HF regardless of the etiology (ischemic or dilated cardiomyopathy), while the expression of NLR family pyrin domain containing 1 (NLRP1) and NLRP3 showed no change in HF samples [131].