Lastly, we performed RIP-Seq analysis for YTHDF3 and then used bioinformatics methods for PPI network analysis to dig the potential downstream target genes (DTGs) of YTHDF3. Thereafter, several DTGs of YTHDF3 comprising mTOR, CD44, ITGB1, ITGAVITGAV, STAT1, and STAT3, etc. were identified to play potential roles in AAA formation and development. The gene discussed is ITGB1; the disease is triple-A syndrome.