Le et al. and Wang et al. illustrated that long non-coding RNA (lncRNA) GAS5 is able to regulate human aortic smooth muscle cells (HASMCs) apoptosis and proliferation through the miR-185-5p/ADCY7miR-185-5p/ADCY7 axis, thus promoting AAA formation (36, 37). This evidence concerns the gene GAS5 and triple-A syndrome.