For the potential roles of YTHDF3 in cardiovascular diseases, genome-wide association studies (GWAS) showed that SNP rs4739066 on YTHDF3 is significantly associated with myocardial infarction (MI) and Shi et al. also found that YTHDF3 is dramatically differentially expressed in MI tissues compared with normal controls (47, 48). This evidence concerns the gene YTHDF3 and myocardial infarction.