The main findings were (i) in T2D patients, hsTNT was negatively correlated with Ktrans and ve, while no such correlation was found for proBNP; (ii) in T2D, hsTNT, Ktrans, and ve were correlated with electrophysiological parameters and an electrophysiology-based neuropathy severity score; and (iii) hsTNT was increased while Ktrans and ve were decreased in DN patients compared to patients without DN. Here, NPPB is linked to neuropathy.