The decreased lipid peroxidation and SOD levels, as the glutathione levels, have increased after honey administration, indicating that the antitumor activity of CDH was due to its antioxidant effect.30 It was shown that the treatment of EAC cells with honey inhibits viability of tumor cells and cell proliferation, while honey pretreatment in EAC mice clearly diminishes tumor size. This evidence concerns the gene CHDH and neoplasm.