The bioinformatic analysis showed that ATF4 had a higher expression in the tissues of patients with lung squamous cell carcinoma (LUSC) and lung adenocarcinoma (LUAD) (Figures 6A, D), and the higher expression of ATF4 was significantly related to longer overall survival (OS) and disease-specific survival (DSS) of NSCLC patients (Figures 6B, C, E, F). The gene discussed is ATF4; the disease is squamous cell lung carcinoma.