MYOCD and non-small cell lung carcinoma: Using CRISPR/Cas9 mediated silencing of Smad3/Smad4, Tong et al. showed decreased mRNA expression of Myocardin (MYOCD) and downregulation of TGF-β Induced invasion and epithelial-mesenchymal transition of non-small cell lung cancer cells (Tong et al., 2020).