Mutations in dynamin 2 gene cause autosomal dominantly inherited diseases, Charcot-Marie-Tooth disease (CMT) (Züchner et al., 2005), and centronuclear myopathy (CNM) (Bitoun et al., 2005), which are characterized by degenerative changes of peripheral nerves and muscles respectively. The gene discussed is DNM2; the disease is Charcot-Marie-Tooth disease.