GSTM1 and Increased total leukocyte count: Leukocytosis (white blood cell [WBC] > 10 × 109/L), thrombocytosis (platelet > 400 × 109/L), and anemia (men: hemoglobin [Hb] < 13.0 g/dL, women: Hb < 12.0 g/dL) were considered abnormal.