HNSCC patients in the subtype of high BAK1 expression included significantly higher infiltration levels of CD8+ T cells (p < 0.05) and neutrophils (p < 0.001) while having a lower infiltration level of B cells (p < 0.001) than did those in the subtype of low BAK1 expression (Figure 8A). The gene discussed is CD8A; the disease is head and neck squamous cell carcinoma.