CDCA3 and renal cell carcinoma: The authors then subcutaneously injected ACHN-R cells into nude mice to establish a xenograft model and demonstrated that tumor growth and sunitinib resistance could be reversed through SNHG12 (a long noncoding RNA) inhibition in vivo, concluding that SNHG12-regulated CDCA3 may be one of the numerous sunitinib-resistant mechanisms in RCC.