Additionally, there was iron overload (p=0.0021) (Figure 6C) and induction of lipid peroxidation (p=0.0011) (Figure 6D) at the implantation sites during infection (p=0.0034), both of which were prevented by HO-1 inhibition treatment (p=0.0307 and 0.0042, respectively). Here, HMOX1 is linked to infection.