However, another murine experiment shows that DCIR1 deficiency is associated to decreased accumulation of neutrophils that shows destructive characteristics and reduced neutrophil-recruiting chemokine MIP-2 in DSS-induced colitis (125), and massive infiltration of neutrophils is known to be associated with the pathogenesis of ulcerative colitis (126) and DSS-induced mice colitis (127). Here, CXCL2 is linked to colitis.