CD274 and glioblastoma: Additionally, researchers have revealed that the expression of the lncRNA MIR155 host gene (MIR155HG) is elevated in GBM tissues in comparison to their equivalent standard counterparts and that its expression is associated with immune checkpoint inhibitors such as Programmed cell death one ligand (PD-L1) and T cell immunoglobulin and mucin domain 3 (TIM-3) in GBM and that its expression is associated with poor prognosis (90).