EGFR and central nervous system cancer: For instance, a study conducted with the primary goal of identifying long non-coding RNA and clarifying its function and mode of action in glioma formation showed that LPP Antisense RNA 2(LPP-AS2) promotes glioma carcinogenesis through a miR-7-5p/EGFR/PI3K/AKT/c-MYC feedback loop (32).